 |
||
|
|
||
|
Page Title:
Dermal Contact with Chemicals in Soil |
||
| |||||||||||||||
|
|
 Dermal Contact with Chemicals in Soil
In order to convert an external dose to an absorbed dose in the dermal
pathway, a dermal absorption factor is applied to the exposure point
concentration. Dermal absorption factors are selected based on structure activity
relationships.
EPCs CF SA AF ABS EF ED
Absorbed Dose(mg / kg - day) =
(E5)
BW AT
where
CS
=
Chemical concentration in soil (mg/kg)
Conversion factor (10-6 kg/mg)
CF
=
Skin surface area available for contact (cm2/event)
SA
=
Soil to skin adherence factor (mg/cm2)
AF
=
ABS =
Absorption factor (unitless)
EF
=
Exposure frequency (events/year)
ED
=
Exposure duration (years)
BW
=
Body weight (kg)
AT
=
Averaging time (period over which exposure is average:
days)
Inhalation
Use measured or modeled air concentrations for comparison to USEPA
reference calculations available in IRIS database at www.epa.gov/ngispgm3/iris.
This is EPA's Integrated Risk Information System (see Appendix B).
E5
Appendix E Human Exposure Equations
|
|
Privacy Statement - Press Release - Copyright Information. - Contact Us - Support Integrated Publishing |
