References - trdoer40162

Mammalian exposure to arsenic occurs primarily through ingestion. Acute

episodes of poisoning are characterized by high mortality and morbidity. Signs

of arsenic toxicosis include intense abdominal pain, staggering gait, extreme

weakness, trembling, salivation, vomiting, diarrhea, prostration, collapse, and

death. Chronic poisoning is infrequently seen due to the fact that excretion and

detoxification are rapid.

References

Agency for Toxic Substances and Disease Registry (ATSDR). (1992).

"Toxicological profile for arsenic," U.S. Public Health Service, Washington,

DC.

Integrated Risk Information System (IRIS). (1999). On-line database, accessed

1999.

Klaassen, Curtis D., Amdur, Mary, and Doull, John. (1995). Toxicology: The

basic science of poisons. 5th ed., McGraw-Hill, New York.

D10

Appendix D Toxicological Profiles