Carcinogenic Risk Estimate for Consumption of Flounder

This is the incremental lifetime average daily intake for the consumption of

commercially harvested flounder using conservative, reasonable maximum

exposure assumptions.

Carcinogenic Risk Estimate for Consumption of

Flounder

ILCR = Lifetime Average Daily Intake H CSF

= 5.6 H 10 -7 mg/kg/day

Lifetime average daily intake

= 7.7 (mg/kg/day) -1

CSF for total PCB

= 4.3 H 10 -6

ILCRI

The USEPA generally considers risks in the range of 10-6 to 10-4 as not

indicating a potential human health risk. Therefore, exposure to total PCBs due to

the proposed dredging project is unlikely to present a carcinogenic risk to the

local human populations. However, this example calculates only risk from

exposure to total PCBs. The summed ICLR due to exposure to PCBs and other

COCs may present an unacceptable risk.

Note that there is uncertainty associated with this risk estimate because the

USEPA currently emphasizes the need for congener specific analyses in

assessing risk from PCB exposure.

F14

Appendix F Hypothetical Example