POINTS OF CONTACT - doerc190010

ERDC TN-DOER-C19

December 2000

further characterize the extent and distribution of the contamination, in a manner similar to that of

the recent field trials of the P450RGS assay.

Finally, by analyzing extracts of organisms living at contaminated sites, both cDNA array and

cell-based assays are capable of discriminating between what is present in the media (sediment, soil,

water) and what is available to the organisms, thus offering substantial savings over the use of chem-

ical analysis and chronic whole-organism bioassays.

POINTS OF CONTACT: For additional information, contact the authors, Dr. Laura S. Inouye

(601-634-2910, ); or Dr. Victor A. McFarland

(601-634-3721, ), or the Program Manager of the

Dredging Operations Environmental Research Program, Dr. Robert M. Engler (601-634-3624,

). This technical note should be cited as follows:

Inouye, L. S., and McFarland, V. A. (2000). "Biomarker-based analysis for contaminants

in sediments/soil: Review of cell-based assays and cDNA arrays," DOER Technical

Notes Collection (ERDC TN-DOER-C19), U.S. Army Engineer Research and

Development Center, Vicksburg, MS. www.wes.army.mil/el/dots/doer

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(Abstract)

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assay," Technical Note DOER-C1, Vicksburg, MS. www.wes.army.mil/el/dots/doer