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 ERDC TN-DOER-R4
September 2004
APPENDIX B
Listing of genes consistently responding at all doses for the given compound/mixture. Fold
induction represents a gene's normalized treatment intensity of the treatment divided by that of
the control. Both fold induction and p-values were calculated by the NLR statistical program of
Kepler et al. (2002).1
Aroclor 1254
Aroclor 1254
Aroclor 1254
Gene
1 g/L (low)
10 g/L (medium)
100 g/L (high)
Location
Gene ID
Fold induction p-value Fold induction p-value Fold induction p-value
Up-regulated genes
B05f
Catenin delta 1/ cadherin-
55
0.037
98
<0.001
74
0.026
associated src substrate
Down-regulated genes
G29
Tubulin alpha 1 (TUBA 1)
0.035
<0.001
0.026
0.002
0.055
0.010
1
References cited in this appendix can be found in the "References" section of the main text.
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